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Safety Information

810118C

Avanti

Egg NBD PE

Avanti Research™ - A Croda Brand 810118C

Synonym(s):

L-α-Phosphatidylethanolamine-N-(7-nitro-2-1,3-benzoxadiazol-4-yl) (Ammonium Salt) (Egg-Transphosphatidylated, Chicken)

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About This Item

Empirical Formula (Hill Notation):
C45H80N5O11P
CAS Number:
477225-98-2
Molecular Weight:
898.12
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (810118C-1mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 810118C

concentration

1 mg/mL (810118C-1mg)

shipped in

dry ice

storage temp.

−20°C

General description

The phosphatidylethanolamine (PE) is a zwitterionic phospholipid. Its headgroup is provided with a phosphate, that is negatively charged and a free amine, that is positively charged. PE is one of the widely distributed glycerophospholipid in eukaryotic cells.

Application

Egg NBD PE is suitable to use as an additive in dimethylformamide (DMF) to compare the effects of nystatin on the diffusion of NBD-Nys and NBD-PE. It has also been used to monitor lipid extraction from liposomes for lipid transfer assay.

Biochem/physiol Actions

Phosphatidylethanolamine (PE) helps to activate factor (F)X and PT, thereby stimulating thrombosis. It serves as an anticoagulant. PE is essential for the surface expression of γ-aminobutyric acid type A receptors (GABAARs) in cultured neurons.

Packaging

5 mL Amber Glass Screw Cap Vial (810118C-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system, Liver,Kidney

WGK

WGK 3

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PRTR

Class I Designated Chemical Substances

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

810118C-1MG:
810118C-BULK:
810118C-VAR:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Lipid-Protein Interactions in Membranes
Yeagle PL
The Membranes of Cells, 291-334 (2016)
Evidence for nystatin micelles in L-cell membranes from fluorescence photobleaching measurements of diffusion
O'Neill LJ, et al.
Biochemistry, 25(1), 177-181 (1986)
Phosphatidylethanolamine metabolism in health and disease
International Review of Cell and Molecular Biology, 321(3), 29-88 (2016)
Antibodies and Diagnostic Tests in Antiphospholipid Syndrome
Systemic Lupus Erythematosus, 495- 501 (2016)
Proteostasis maintenance of Cys-loop receptors
Advances in Protein Chemistry and Structural Biology, 103(3), 1-23 (2016)
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