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KITALYSIS-BOR

Sigma-Aldrich

KitAlysis High-Throughput Miyaura Borylation Reaction Screening Kit-Pack of 2

reaction suitability

reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Cross Couplings
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: catalyst
core: palladium

functional group

phosphine

Application

Screening kit for Miyaura borylation reaction. Step-by-step user guides and a downloadable experimental excel sheets are provided in the below hyperlinks.
Step-by-Step Guide for Miyaura Borylation Reaction Screening Kit
Downloadable Experiment excel sheets

Each kit contains 2 customizable screening sets that include the following components:
  • 6 x 4 pre-weighed catalysts in glass vials loaded with stir bars and topped with cap mat.
  • 4 x 4 mL reaction vials with pre-weighed KOAc
  • Bis(pinacolato)diboron (473294), tetrahydroxydiboron (754242), and pinacol (221171)
  • 1 (2 mL) ampule each of toluene, THF, n-butanol, DMA, MeOH, MeCN, ethylene glycol and DIPEA.
  • 1 NEW KitAlysis 24-Well Reaction Block Replacement Film.
  • 4 stir bars for substrate stock solution vials.
  • 1 internal standard.

Best when used with KitAlysis Benchtop Inertion Box and 24-well Reaction Block (sold separately).

Features and Benefits

  • Designed and tested by synthetic chemists.
  • Easily run 24-microscale reactions in parallel.
  • 10 μmol reactions with 1 μmol catalyst, 3 equiv. base, 0.1 M concentration.
  • Customizable Excel Template for quick calculations and easy incorporation into electronic laboratory notebooks.

Legal Information

KitAlysis is a trademark of Sigma-Aldrich Co. LLC

Kit Components Also Available Separately

Product No.
Description
SDS

  • 764175P(Cy3) Pd G3, 97%

  • 791733Potassium acetate, anhydrous, free-flowing, Redi-Dri, ACS reagent, ≥99.0%

  • 804274XPhos Pd G4, 95%

  • 804282SPhos Pd G4

  • 804290RuPhos Pd G4

  • 804975DTBPF-Pd-G3

  • 900349cataCXium Pd G4

  • 900522Toluene, anhydrous, ZerO2®, 99.8%

  • 900631Ethylene glycol, anhydrous, ZerO2®, 99.8%

  • 900634N,N-Dimethylacetamide, anhydrous, ZerO2®, 99.8%

  • 900636Tetrahydrofuran, anhydrous, inhibitor-free, ZerO2®, ≥99.9%

  • 9006391-Butanol, anhydrous, ZerO2®, 99.8%

  • 900641Methanol, anhydrous, ZerO2®, 99.8%

  • 900644Acetonitrile, anhydrous, ZerO2®, 99.8%

  • 900690N,N-Diisopropylethylamine, purified by redistillation, ZerO2®, 99.5%

  • 221171Pinacol, 98%

  • 473294Bis(pinacolato)diboron, 99%

  • 754242Tetrahydroxydiboron, 95%

  • B34656Biphenyl, ReagentPlus®, 99.5%

  • Z118850Spinbar® magnetic stirring fleas, red, L 10 mm, diam. 3 mm

  • Z742110KitAlysis 24-well reaction block replacement film

See All (21)

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Repr. 1B - Skin Irrit. 2 - STOT RE 2 Oral - STOT SE 1

Target Organs

Kidney

Supplementary Hazards

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

1.4 °F

Flash Point(C)

-17 °C

Certificate of Analysis

Certificate of Origin

Quotes and Ordering

Articles

KitAlysis™ High-Throughput Screening Platform

KitAlysis High-Throughput Screening Kits provide solution to efficiently identify or optimize suitable catalytic reaction conditions. Chemist can rapidly run 24 unique micro scale reactions in parallel with tailored conditions.

Protocols

Catalyst Screening followed by TLC-MS for Reaction Progress Analysis using KitAlysis™

Catalyst screening, KitAlysis™ High-Throughput Screening Kits, Thin layer chromatography (TLC), parallel analysis, parallel synthesisigh-Throughput Buchwald-Hartwig Amination Reaction Screening Kit, TLC-MS analysis

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