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KITALYSIS-BOR

Sigma-Aldrich

KitAlysis High-Throughput Miyaura Borylation Reaction Screening Kit-Pack of 2

reaction suitability

reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Cross Couplings
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: catalyst
core: palladium

functional group

phosphine

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KITALYSIS-SMKITALYSIS-RCMKITALYSISBASE
reaction suitability

reaction type: Buchwald-Hartwig Cross Coupling Reaction, reaction type: Cross Couplings, reaction type: Heck Reaction, reaction type: Hiyama Coupling, reaction type: Negishi Coupling, reaction type: Sonogashira Coupling, reaction type: Stille Coupling, reaction type: Suzuki-Miyaura Coupling, reagent type: catalyst
core: palladium

reaction suitability

reaction type: Cross Couplings, reaction type: Suzuki-Miyaura Coupling, reagent type: catalyst
core: palladium

reaction suitability

-

reaction suitability

reaction type: Buchwald-Hartwig Cross Coupling Reaction, reaction type: Cross Couplings, reaction type: Heck Reaction, reaction type: Hiyama Coupling, reaction type: Negishi Coupling, reaction type: Sonogashira Coupling, reaction type: Stille Coupling, reaction type: Suzuki-Miyaura Coupling

functional group

phosphine

functional group

phosphine

functional group

-

functional group

phosphine

Application

Screening kit for Miyaura borylation reaction. Step-by-step user guides and a downloadable experimental excel sheets are provided in the below hyperlinks.
Step-by-Step Guide for Miyaura Borylation Reaction Screening Kit
Downloadable Experiment excel sheets

Each kit contains 2 customizable screening sets that include the following components:
  • 6 x 4 pre-weighed catalysts in glass vials loaded with stir bars and topped with cap mat.
  • 4 x 4 mL reaction vials with pre-weighed KOAc
  • Bis(pinacolato)diboron (473294), tetrahydroxydiboron (754242), and pinacol (221171)
  • 1 (2 mL) ampule each of toluene, THF, n-butanol, DMA, MeOH, MeCN, ethylene glycol and DIPEA.
  • 1 NEW KitAlysis 24-Well Reaction Block Replacement Film.
  • 4 stir bars for substrate stock solution vials.
  • 1 internal standard.
Monitor reaction progress via TLC-MS by following this protocol

Best when used with KitAlysis Benchtop Inertion Box and 24-well Reaction Block (sold separately).

Features and Benefits

  • Designed and tested by synthetic chemists.
  • Easily run 24-microscale reactions in parallel.
  • 10 μmol reactions with 1 μmol catalyst, 3 equiv. base, 0.1 M concentration.
  • Customizable Excel Template for quick calculations and easy incorporation into electronic laboratory notebooks.

Legal Information

KitAlysis is a trademark of Sigma-Aldrich Co. LLC

Kit Components Also Available Separately

Product No.
Description
SDS

  • 764175P(Cy3) Pd G3, 97%SDS

  • 791733Potassium acetate, anhydrous, free-flowing, Redi-Dri, ACS reagent, ≥99.0%SDS

  • 804274XPhos Pd G4, 95%SDS

  • 804282SPhos Pd G4SDS

  • 804290RuPhos Pd G4SDS

  • 804975DTBPF-Pd-G3SDS

  • 900349cataCXium Pd G4SDS

  • 900522Toluene, anhydrous, ZerO2®, 99.8%SDS

  • 900631Ethylene glycol, anhydrous, ZerO2®, 99.8%SDS

  • 900634N,N-Dimethylacetamide, anhydrous, ZerO2®, 99.8%SDS

  • 900636Tetrahydrofuran, anhydrous, inhibitor-free, ZerO2®, ≥99.9%SDS

  • 9006391-Butanol, anhydrous, ZerO2®, 99.8%SDS

  • 900641Methanol, anhydrous, ZerO2®, 99.8%SDS

  • 900644Acetonitrile, anhydrous, ZerO2®, 99.8%SDS

  • 900690N,N-Diisopropylethylamine, purified by redistillation, ZerO2®, 99.5%SDS

  • 221171Pinacol, 98%SDS

  • 473294Bis(pinacolato)diboron, 99%SDS

  • 754242Tetrahydroxydiboron, 95%SDS

  • B34656Biphenyl, ReagentPlus®, 99.5%SDS

  • Z118850Spinbar® magnetic stirring fleas, red, L 10 mm, diam. 3 mmSDS

  • Z742110KitAlysis 24-well reaction block replacement filmSDS

See All (21)

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Repr. 1B - Skin Irrit. 2 - STOT RE 2 Oral - STOT SE 1

Target Organs

Kidney

Supplementary Hazards

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

1.4 °F

Flash Point(C)

-17 °C


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PDSCL

Please refer to KIT Component information

PRTR

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FSL

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ISHL Indicated Name

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ISHL Notified Names

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Cartagena Act

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JAN Code

キットコンポーネントの情報を参照してください


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