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Safety Information

937762

Sigma-Aldrich

Linear polyethyleneimine-block-poly(ethylene glycol)

PEG average Mn 5000, PEI average Mn 20000

Synonym(s):

PEG-PEI, PEG-b-PEI, Poly(ethylene glycol)-block-polyethylenimine

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About This Item

Linear Formula:
CH3(C2H4O)n(C2H5N)mOH
UNSPSC Code:
12352125
NACRES:
NA.21

form

powder or solid

Quality Level

100

mol wt

PEG average Mn 5000
PEI average Mn 20000

color

white to pale yellow

storage temp.

2-8°C

Related Categories

Application

Due to their low immunogenicity profiles, polymeric non viral vectors have shown promise in advancing the treatment of many severe genetic and acquired diseases via gene therapy. Poly(ethyleneimine) is one of the most commonly used cationic polymers for gene delivery applications. Copolymers of PEI and hydrophilic poly(ethylene glycol) have been designed to provide a stealth-like shield around polymer/DNA complexes, reducing nonspecific interactions, inhibiting activation of the reticuloendothelial system, and prolonging the half-life of the complexes in the blood.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

937762-500MG:
937762-VAR:
937762-BULK:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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