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Merck

SPOP

speckle-type POZ protein

Synonyms:
BTBD32, TEF2
Species:
UniProtKB ID:
Gene ID:
  • Human(8405) Summary: This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
  • Mouse(20747) speckle-type POZ protein
  • Rat(287643) speckle-type POZ protein
  • Zebrafish(100005514) speckle-type POZ protein
  • chicken(425528) speckle-type POZ protein
  • dog(480548) speckle-type POZ protein
  • domestic cat(101094712) speckle-type POZ protein
  • Horse(100056116) speckle-type POZ protein
  • domestic guinea pig(100713182) speckle-type POZ protein
  • naked mole-rat(101725604) speckle-type POZ protein
  • Domestic Rabbit(100343929) speckle-type POZ protein
  • cow(530618) speckle-type POZ protein
  • sheep(101111300) speckle-type POZ protein

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-SPOP antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-SPOP antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Monoclonal Anti-SPOP, (C-terminal) antibody produced in mouse, clone 3E2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-SPOP Antibody, clone 2N8L8, Rabbit Monoclonal, ,
Species Reactivity
human
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human SPOP,
Species
human
MISSION® esiRNA, targeting mouse Spop,
Species
mouse