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Merck

RNF7

ring finger protein 7

Synonyms:
CKBBP1, ROC2, SAG
Species:
UniProtKB ID:
Gene ID:
  • Human(9616) Summary: The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
  • Mouse(19823) ring finger protein 7
  • Rat(300948) ring finger protein 7
  • Zebrafish(503534) ring finger protein 7
  • domestic cat(101097835) ring finger protein 7
  • dog(477097) ring finger protein 7
  • chicken(424781) ring finger protein 7
  • domestic guinea pig(100735307) ring finger protein 7
  • naked mole-rat(101696646) ring finger protein 7
  • sheep(101106816) ring finger protein 7

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-RNF7 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
western blot
Anti-RNF7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human RNF7 (2),
Species
human
MISSION® esiRNA, targeting human RNF7 (1),
Species
human