RBPJ
recombination signal binding protein for immunoglobulin kappa J region
Synonyms:
AOS3, CBF1, IGKJRB, IGKJRB1, KBF2, RBP-J, RBPJK, RBPSUH, SUH, csl
Species:
Human RBPJ (3516), Mouse Rbpj (19664), Rat Rbpj (679028), chicken RBPJ (422802), Horse RBPJ (100055547), domestic cat RBPJ (101100207), dog RBPJ (479122), domestic guinea pig Rbpj (100716535), naked mole-rat Rbpj (101726624), cow RBPJ (767928)
UniProtKB ID:
Gene ID:
- Human(3516) Summary: The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway. The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins. It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes. Also, this protein can bind specifically to the recombination signal sequence of immunglobulin kappa type J segments. Several transcript variants encoding different isoforms have been found for this gene, and several pseudogenes of this gene exist on chromosome 9. [provided by RefSeq, Oct 2011]
- Mouse(19664) recombination signal binding protein for immunoglobulin kappa J region
- Rat(679028) recombination signal binding protein for immunoglobulin kappa J region
- chicken(422802) recombination signal binding protein for immunoglobulin kappa J region
- Horse(100055547) recombination signal binding protein for immunoglobulin kappa J region
- domestic cat(101100207) recombination signal binding protein for immunoglobulin kappa J region
- dog(479122) recombination signal binding protein for immunoglobulin kappa J region
- domestic guinea pig(100716535) recombination signal binding protein for immunoglobulin kappa J region
- naked mole-rat(101726624) recombination signal binding protein for immunoglobulin kappa J region
- cow(767928) recombination signal binding protein for immunoglobulin kappa J region
- sheep(101107196) recombination signal binding protein for immunoglobulin kappa J region
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-RBP-Jk Antibody, Chemicon®, from rabbit,
Species Reactivity
human, mouse
Application
ChIP
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-RBPJK antibody produced in rabbit, ,
Species Reactivity
mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-RBPJ Antibody, serum, from rabbit,
Species Reactivity
human, mouse, primate
Application
ChIP
western blot
western blot
Anti-RBP-Jk, clone 1F1 Antibody, clone 1F1, from rat,
Species Reactivity
drosophila, human
Application
ChIP
electrophoretic mobility shift assay
immunoprecipitation (IP)
electrophoretic mobility shift assay
immunoprecipitation (IP)
Anti-RBPJ antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence