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Merck

PKM

pyruvate kinase, muscle

Synonyms:
CTHBP, OIP3, PK3, PKM2, TCB, THBP1
Species:
UniProtKB ID:
Gene ID:
  • Human(5315) Summary: This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported. [provided by RefSeq, May 2011]
  • Mouse(18746) pyruvate kinase, muscle
  • Rat(25630) pyruvate kinase, muscle
  • cow(512571) pyruvate kinase, muscle
  • sheep(101109180) pyruvate kinase, muscle
  • Domestic Rabbit(100008676) pyruvate kinase, muscle
  • naked mole-rat(101721034) pyruvate kinase, muscle
  • domestic guinea pig(100736056) pyruvate kinase, muscle
  • Horse(100063687) pyruvate kinase, muscle
  • domestic cat(101092521) pyruvate kinase, muscle
  • dog(403874) pyruvate kinase, muscle

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PKM1 Antibody, serum, from rabbit,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot
Anti-PKM2 Antibody, serum, from rabbit,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-PKM2 Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
bovine, horse, human, monkey, mouse, rat
Application
immunocytochemistry
western blot
ANTI-PKM1 (C-TERM L398) antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot
Anti-PKM1 Antibody, clone 1B15 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse
Application
affinity binding assay
immunohistochemistry

western blot

Proteins

Product Number
Description
Species
PKM1 active human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human PKM,
Species
human