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Merck

IL18BP

interleukin 18 binding protein

Synonyms:
IL18BPa
Species:
UniProtKB ID:
Gene ID:
  • Human(10068) Summary: The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]
  • Mouse(16068) interleukin 18 binding protein
  • Rat(84388) interleukin 18 binding protein
  • domestic guinea pig(100714819) interleukin 18 binding protein
  • naked mole-rat(101721919) interleukin 18 binding protein
  • sheep(101118983) interleukin 18 binding protein
  • cow(617470) interleukin 18 binding protein
  • domestic cat(101096599) interleukin 18 binding protein
  • dog(476818) interleukin 18 binding protein

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ELISA

Product Number
Description
Species
Human IL-18 BPa  ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-IL18BP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-IL18BP antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Monoclonal Anti-IL18BP antibody produced in mouse, clone 2A9, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot

Proteins

Product Number
Description
Species
IL18BP human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human IL18BP,
Species
human
MISSION® esiRNA, targeting mouse Il18bp,
Species
mouse