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Merck

EIF5B

eukaryotic translation initiation factor 5B

Synonyms:
IF2
Species:
UniProtKB ID:
Gene ID:
  • Human(9669) Summary: Accurate initiation of translation in eukaryotes is complex and requires many factors, some of which are composed of multiple subunits. The process is simpler in prokaryotes which have only three initiation factors (IF1, IF2, IF3). Two of these factors are conserved in eukaryotes: the homolog of IF1 is eIF1A and the homolog of IF2 is eIF5B. This gene encodes eIF5B. Factors eIF1A and eIF5B interact on the ribosome along with other initiation factors and GTP to position the initiation methionine tRNA on the start codon of the mRNA so that translation initiates accurately. [provided by RefSeq, Jul 2008]
  • Mouse(226982) eukaryotic translation initiation factor 5B
  • Rat(308306) eukaryotic translation initiation factor 5B
  • Zebrafish(561194) eukaryotic translation initiation factor 5B
  • domestic cat(101095815) eukaryotic translation initiation factor 5B
  • cow(532850) eukaryotic translation initiation factor 5B
  • Horse(100050422) eukaryotic translation initiation factor 5B
  • dog(474556) eukaryotic translation initiation factor 5B
  • fruit fly(44261) CG10840 gene product from transcript CG10840-RE
  • chicken(395514) eukaryotic translation initiation factor 5B
  • sheep(101106067) eukaryotic translation initiation factor 5B
  • naked mole-rat(101699308) eukaryotic translation initiation factor 5B
  • domestic guinea pig(100719329) eukaryotic translation initiation factor 5B

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-EIF5B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Monoclonal Anti-EIF5B antibody produced in mouse, clone 3F9, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Anti-EIF5B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Eif5b,
Species
mouse
MISSION® esiRNA, targeting human EIF5B,
Species
human