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Merck

ABL2

c-abl oncogene 2, non-receptor tyrosine kinase

Synonyms:
ABLL, ARG
Species:
UniProtKB ID:
Gene ID:
  • Human(27) Summary: This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to the c-abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 domains, and it plays a role in cytoskeletal rearrangements through its C-terminal F-actin- and microtubule-binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ets variant 6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2009]
  • Mouse(11352) v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene)
  • Rat(304883) c-abl oncogene 2, non-receptor tyrosine kinase
  • sheep(101121110) v-abl Abelson murine leukemia viral oncogene homolog 2
  • Domestic Rabbit(100348328) v-abl Abelson murine leukemia viral oncogene homolog 2
  • domestic guinea pig(100714234) v-abl Abelson murine leukemia viral oncogene homolog 2
  • naked mole-rat(101704827) v-abl Abelson murine leukemia viral oncogene homolog 2
  • Zebrafish(570636) v-abl Abelson murine leukemia viral oncogene homolog 2
  • cow(511845) v-abl Abelson murine leukemia viral oncogene homolog 2
  • Horse(100053033) v-abl Abelson murine leukemia viral oncogene homolog 2
  • domestic cat(101080757) v-abl Abelson murine leukemia viral oncogene homolog 2
  • chicken(395410) v-abl Abelson murine leukemia viral oncogene homolog 2
  • dog(480052) v-abl Abelson murine leukemia viral oncogene homolog 2

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-ABL2 antibody produced in mouse, clone 5C6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot
ANTI-ABL2 antibody produced in mouse, clone 2H8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-ABL2 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
ANTI-ABL2 antibody produced in mouse, clone 5C7, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
ANTI-ABL2 antibody produced in mouse, clone 3G3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot

Proteins

Product Number
Description
Species
ABL2 (38-end), active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
Arg Protein, active, 10 µg, Active, N-terminal His6-tagged, recombinant amino acids, 27-end, mouse Arg, for use in Kinase Assays.,
Species
mouse
Arg Protein, active, human, 10 µg, ,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human ABL2,
Species
human