Research has shown that hyperpolarizing stable isotope-labeled metabolites, such as pyruvic acid-1-13C prior to Magnetic Resonance Imaging (MRI) increases sensitivity by > 10,000x over conventional MRI. This allows researchers to detect areas of altered metabolism, which is indicative of the presence of cancer. Additionally, differences in perfusion often associated with cancer can be observed with the use of isotope-labeled metabolically inactive agents, such as urea-13C,15N2.
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University of California, San Francisco
Postdoctoral Researcher, UCSF Bioengineering
Research and disease areas