GPR62 constitutively activates cAMP signaling but is dispensable for male fertility in mice.

GPR62 constitutively activates cAMP signaling but is dispensable for male fertility in mice.

Reproduction (Cambridge, England) (2017-09-16)

Tomoyuki Muroi, Yuri Matsushima, Ryota Kanamori, Hikari Inoue, Wataru Fujii, Keiichiro Yogo

ABSTRACT

G-protein-coupled receptors (GPCRs) participate in diverse physiological functions and are promising targets for drug discovery. However, there are still over 140 orphan GPCRs whose functions remain to be elucidated.

MATERIALI

N° Catalogo

Marchio

Descrizione del prodotto

D5796

Sigma-Aldrich

Terreno Eagle modificato di Dulbecco - alto glucosio, With 4500 mg/L glucose, L-glutamine, and sodium bicarbonate, without sodium pyruvate, liquid, sterile-filtered, suitable for cell culture

A5955

Sigma-Aldrich

Soluzione di antimicotico antibiotico (100×), stabilizzata, with 10,000 units penicillin, 10 mg streptomycin and 25 μg amphotericin B per mL, 0.1 μm filtered, BioReagent, suitable for cell culture