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Merck

Improved synthesis of chalcones under ultrasound irradiation.

Ultrasonics sonochemistry (2002-10-10)
Ji-Tai Li, Wen-Zhi Yang, Shu-Xiang Wang, Sheng-Hui Li, Tong-Shuang Li
ABSTRACT

Claisen-Schmidt condensation of acetophenone with aromatic aldehydes catalyzed by pulverized KOH and KF-Al2O3 results chalcones in 52-97% and 83-98% yields respectively in alcoholic solvent under ultrasound irradiation.

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