Conjugate addition of lithiated methyl pyridines to enones.

Conjugate addition of lithiated methyl pyridines to enones.

The Journal of organic chemistry (2010-08-14)

Douglass F Taber, Pengfei Guo, Michael T Pirnot

PMID20704446

ABSTRACT

Preparatively useful conjugate addition of lithiated methyl pyridines to cyclic and acyclic enones is reported. Addition of 2-picoline to 3-penten-2-one led to a concise synthesis of the alkaloids (+/-)-senepodine G and (+/-)-cermizine C.

MATERIALI

N° Catalogo

Marchio

Descrizione del prodotto

145017

Sigma-Aldrich

3-Penten-2-one, 70%