Passa al contenuto
Merck
Tutte le immagini(4)

Documenti

V1255

Sigma-Aldrich

D-Valine

BioReagent, suitable for cell culture

Sinonimo/i:

(R)-α-Aminoisovaleric acid, D-2-Amino-3-methylbutanoic acid

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
Tutte le immagini(4)

About This Item

Formula condensata:
(CH3)2CHCH(NH2)CO2H
Numero CAS:
640-68-6
Peso molecolare:
117.15
Beilstein:
1721135
Numero CE:
211-368-9
Numero MDL:
MFCD00064219
Codice UNSPSC:
12352209
ID PubChem:
24900713
NACRES:
NA.75

Origine biologica

synthetic (organic)

Nome Commerciale

BioReagent

Forma fisica

powder

tecniche

cell culture | mammalian: suitable

Punto di fusione

>295 °C (subl.) (lit.)

Condizioni di spedizione

ambient

Temperatura di conservazione

room temp

Stringa SMILE

CC(C)[C@@H](N)C(O)=O

InChI

1S/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8)/t4-/m1/s1
KZSNJWFQEVHDMF-SCSAIBSYSA-N

Cerchi prodotti simili? Visita Guida al confronto tra prodotti

Descrizione generale

L-Valine is an essential non-polar amino acid. D-Valine is the non-proteinogenic isomer of valine.

Applicazioni

D-Valine has been used as a supplement in:
  • Dulbecco′s modified Eagle′s medium (DMEM)/Nutrient Mixture F-12 Ham (F-12) for mice renal proximal tubule cell (RPTC) culture
  • endothelial cell growth medium MV2 for rat lung microvascular endothelial cell (RLMEC) culture
  • DMEM/F-12 for mouse tracheal epithelial cell (MTEC) culture

Azioni biochim/fisiol

D-Valine has a broad range of industrial applications such as semi-synthetic veterinary antibiotics, pharmaceutical drugs, and agricultural pesticides.
D-valine is used in cell culture as a selective inhibitor of cell proliferation, wherein it inhibits cells that lack the enzyme D-amino acid oxidase. Historically D-valine has been used to inhibit fibroblast growth while allowing selective growth of epithelial cells.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

I clienti hanno visto anche

Slide 1 of 4

1 of 4

Ethylene glycol-bis(succinic acid N-hydroxysuccinimide ester) powder

Sigma-Aldrich

E3257

Ethylene glycol-bis(succinic acid N-hydroxysuccinimide ester)

D-Proline ReagentPlus®, ≥99%

Sigma-Aldrich

858919

D-Proline

D-Alanine ≥98% (HPLC)

Sigma-Aldrich

A7377

D-Alanine

L-Leucine reagent grade, ≥98% (HPLC)

Sigma-Aldrich

L8000

L-Leucine

Elham Mohammadi et al.
Cell and tissue research, 362(3), 597-609 (2015-06-13)
Efficacy of therapeutic angiogenesis needs a comprehensive understanding of endothelial cell (EC) function and biological factors and cells that interplay with ECs. Stem cells are considered the key components of pro- and anti-angiogenic milieu in a wide variety of physiopathological
V A Lazzaro et al.
Research communications in chemical pathology and pharmacology, 75(1), 39-48 (1992-01-01)
A selective cell culture medium, D-valine minimal essential medium (92 mg/l), has been developed to inhibit the proliferation of fibroblasts in cell culture (Gilbert & Migeon 1975). Substitution of D-valine for L-valine prevents fibroblast growth due to the absence of
Ming Chen et al.
World journal of microbiology & biotechnology, 32(10), 171-171 (2016-08-28)
D-Valine is an important organic chiral source and has extensive industrial application, which is used as intermediate for the synthesis of agricultural pesticides, semi-synthetic veterinary antibiotics and pharmaceutical drugs. Its derivatives have shown great activity in clinical use, such as
Hui Li et al.
PLoS pathogens, 14(1), e1006821-e1006821 (2018-01-05)
The highly pathogenic avian influenza (HPAI) H5N1 influenza virus has been a public health concern for more than a decade because of its frequent zoonoses and the high case fatality rate associated with human infections. Severe disease following H5N1 influenza
Phillip C Calder
The Journal of nutrition, 136(1 Suppl), 288S-293S (2005-12-21)
Although there has been great interest in the effects of amino acids on immune function, little is known about the impact of changes in BCAA availability on the ability of the immune system to function. Human immune cells incorporate BCAA
Visualizza tutti i documenti correlati

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.