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SML2107

Sigma-Aldrich

Tulathromycin A

≥95% (HPLC), powder, macrolide antibiotic

Sinonimo/i:

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[[2,6-dideoxy-3-C-methyl-3-O-methyl-4-C-[(propylamino)methyl]-a-L-ribo-hexopyranosyl]oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-b-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one, CP-472295

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About This Item

Formula empirica (notazione di Hill):
C41H79N3O12
Numero CAS:
217500-96-4
Peso molecolare:
806.08
Numero MDL:
MFCD09838804
Codice UNSPSC:
12352200
NACRES:
NA.77

product name

Tulathromycin A, ≥95% (HPLC)

Saggio

≥95% (HPLC)

Forma fisica

powder

Condizioni di stoccaggio

desiccated

Colore

white to beige

Solubilità

DMSO: 2 mg/mL, clear

Temperatura di conservazione

−20°C

Stringa SMILE

C[C@@]([C@H](OC([C@@H]([C@H]1O[C@]2([H])O[C@@H](C)[C@@](O)(CNCCC)[C@@](C2)(OC)C)C)=O)CC)([C@@H]([C@H](NC[C@H](C)C[C@]([C@@H]([C@H]1C)O[C@]3([H])O[C@H](C)C[C@H](N(C)C)[C@H]3O)(O)C)C)O)O

InChI

1S/C41H79N3O12/c1-15-17-42-22-41(50)28(8)53-31(20-39(41,10)51-14)55-33-25(5)35(56-37-32(45)29(44(12)13)18-24(4)52-37)38(9,48)19-23(3)21-43-27(7)34(46)40(11,49)30(16-2)54-36(47)26(33)6/h23-35,37,42-43,45-46,48-50H,15-22H2,1-14H3/t23-,24-,25+,26-,27-,28+,29+,30-,31+,32-,33+,34-,35-,37+,38-,39-,40-,41+/m1/s1
GUARTUJKFNAVIK-QPTWMBCESA-N

Azioni biochim/fisiol

Tulathromycin A is a macrolide antibiotic. It binds to the subunit 50S of the bacterial ribosome, interfering with bacterial protein synthesis.
Tulathromycin is a triamilide antimicrobial, which is structurally similar to the di-basic azalide antibiotic azithromycin. It is used to treat bovine and swine bacterial respiratory diseases.

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H317,H319,H412

Classi di pericolo

Aquatic Chronic 3 - Eye Irrit. 2 - Skin Sens. 1

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Nigel A Evans
Veterinary therapeutics : research in applied veterinary medicine, 6(2), 83-95 (2005-08-12)
Tulathromycin is a novel triamilide antimicrobial that has been approved for use in the treatment and prevention of bovine respiratory disease and the treatment of swine respiratory disease in the European Union and the United States. The agent penetrates gram-negative
Nicolas Villarino et al.
Veterinary journal (London, England : 1997), 198(2), 352-357 (2013-11-26)
Tulathromycin is the first and only member of the triamilide sub-class of macrolides that is used therapeutically and has been registered in more than 30 countries across America, Europe, Oceania and Asia. The discovery of tulathromycin and its registration in
Qiaoyi Zhou et al.
Frontiers in pharmacology, 8, 392-392 (2017-07-14)
Tulathromycin, a macrolide antibiotic, is used for the treatment of respiratory disease in cattle and swine. The aim of our study was to investigate the
Haihong Hao et al.
Frontiers in microbiology, 7, 477-477 (2016-04-20)
To evaluate microbiological safety of tulathromycin on human intestinal bacteria, tulathromycin (0, 0.1, 1, 10, and 100 μg/mL) was added into Chemostats. Before and after drug exposure, we monitored (1) population, SCFA products, antimicrobial resistance, and colonization resistance of gut
Diana Gáler et al.
Journal of agricultural and food chemistry, 52(8), 2179-2191 (2004-04-15)
Tulathromycin is a novel member of the triamilide class of antibiotics that was developed as a safe and effective single-dose treatment of bovine and porcine respiratory disease. An accurate and precise analytical method was developed for the extraction and measurement
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