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Merck
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Documenti

C7397

Sigma-Aldrich

Cyclophosphamide monohydrate

ISOPAC®

Sinonimo/i:

2-[Bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide, Cytoxan

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About This Item

Formula empirica (notazione di Hill):
C7H15Cl2N2O2P · H2O
Numero CAS:
6055-19-2
Peso molecolare:
279.10
Beilstein:
4678992
Numero CE:
200-015-4
Numero MDL:
MFCD00149395
Codice UNSPSC:
51112507
ID PubChem:
24892961
NACRES:
NA.25

Saggio

97.0-103.0% (HPLC)

Forma fisica

powder

Punto di fusione

49-51 °C (lit.)

Temperatura di conservazione

2-8°C

Stringa SMILE

[H]O[H].ClCCN(CCCl)P1(=O)NCCCO1

InChI

1S/C7H15Cl2N2O2P.H2O/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14;/h1-7H2,(H,10,12);1H2
PWOQRKCAHTVFLB-UHFFFAOYSA-N

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Applicazioni

Cyclophosphamide, a nitrogen mustard DNA alkylating agent, is used to study its mechanisms of action as an anticancer and antiimmunity drug.

Azioni biochim/fisiol

Cyclophosphamide is a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity.

Confezionamento

Packaged in a 100 mL serum bottle with silicon/PTFE septum and aluminum tear seal.

Avvertenza

Injecting a compatible solvent directly into the vial permits preparation of any desired strength solution without exposure.

Ricostituzione

Dissolving the contents in 100 mL of solvent yields a 1% solution.

Note legali

Isopac is a registered trademark of Merck KGaA, Darmstadt, Germany

ISOPAC

N° Catalogo
Descrizione
Determinazione del prezzo

Pittogrammi

Skull and crossbonesHealth hazard
GHS06,GHS08

Avvertenze

Danger

Indicazioni di pericolo

H301,H340,H350,H360FD

Classi di pericolo

Acute Tox. 3 Oral - Carc. 1B - Muta. 1B - Repr. 1A

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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