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Documenti

A4625

Sigma-Aldrich

N-Acetyl-L-alanine

~99%

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About This Item

Formula empirica (notazione di Hill):
C5H9NO3
Numero CAS:
97-69-8
Peso molecolare:
131.13
Numero CE:
202-602-0
Numero MDL:
MFCD00063132
Codice UNSPSC:
12352209
eCl@ss:
32160406
ID PubChem:
24890887
NACRES:
NA.26

product name

N-Acetyl-L-alanine, ~99%

Saggio

~99%

Forma fisica

powder

Colore

white to off-white

applicazioni

cell analysis

Temperatura di conservazione

2-8°C

Stringa SMILE

C[C@H](NC(C)=O)C(O)=O

InChI

1S/C5H9NO3/c1-3(5(8)9)6-4(2)7/h3H,1-2H3,(H,6,7)(H,8,9)/t3-/m0/s1
KTHDTJVBEPMMGL-VKHMYHEASA-N

Applicazioni

N-Acetyl-L-alanine has been used to study its effect on cytosolic and mitochondrial reduction-oxidation sensitive green fluorescent protein (roGFP).

Azioni biochim/fisiol

N-Acetyl-L-alanine may be used with other L-aminoacylated amino acids as a substrate for the identification, differentiation and characterization of aminoacylase(s)/amidohydrolase(s).

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

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Supelco

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Sigma-Aldrich

CDS020792

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Sigma-Aldrich

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Eiko Suzuki et al.
European journal of drug metabolism and pharmacokinetics, 42(6), 965-972 (2017-04-28)
Human in vitro and dog in vitro/in vivo researches indicate that the drug-drug interaction (DDI) of decreased plasma valproic acid (VPA) concentration by co-administration of carbapenem antibiotics is caused by inhibition of acylpeptide hydrolase (APEH)-mediated VPA acylglucuronide (VPA-G) hydrolysis by
Kevin Bray et al.
PloS one, 7(7), e41831-e41831 (2012-08-01)
mTOR inhibitors are used clinically to treat renal cancer but are not curative. Here we show that autophagy is a resistance mechanism of human renal cell carcinoma (RCC) cell lines to mTOR inhibitors. RCC cell lines have high basal autophagy
Linda Chang et al.
Biological psychiatry, 62(12), 1396-1404 (2007-08-19)
Abnormalities in the white matter of the brain may occur in individuals with schizophrenia as well as with normal aging. Therefore, elderly schizophrenic patients may suffer further cognitive decline as they age. This study determined whether elderly schizophrenia participants, especially
Bram Boeckx et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 86, 366-374 (2011-11-18)
The conformational landscape of N-acetylalanine has been investigated by a theoretical and matrix-isolation FT-IR study. Optimizations of N-acetylalanine structures has been conducted at successive higher levels of theory HF/3-21G, DFT(B3LYP)/6-31++G** and MP2/6-31++G**. This resulted in three stable conformations. Among these
C Bruyneel et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 56(3), 591-602 (2000-05-04)
The energies, vibrational frequencies and IR intensities of cis- and trans-N-acetyl-L-alanine (NAAL) are computed using the density functional theory (B3LYP) combined with the 6-311G(d, p) basis set. The trans conformer is characterized by an intramolecular NH ... O hydrogen bond
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