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D2388

Sigma-Aldrich

Dimethyl 3,3′-dithiopropionimidate dihydrochloride

powder

Sinonimo/i:

DTBP, Dimethyl 3,3′-dithio-bis(propionimidate) dihydrochloride, Wang/Richards’ reagent

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About This Item

Formula empirica (notazione di Hill):
C8H16N2O2S2 · 2HCl
Numero CAS:
Peso molecolare:
309.28
Numero MDL:
Codice UNSPSC:
12352116
ID PubChem:
NACRES:
NA.22

Forma fisica

powder

Impiego in reazioni chimiche

reagent type: cross-linking reagent

Solubilità

H2O: 50 mg/mL

Temperatura di conservazione

2-8°C

Stringa SMILE

Cl.Cl.COC(=N)CCSSCCC(=N)OC

InChI

1S/C8H16N2O2S2.2ClH/c1-11-7(9)3-5-13-14-6-4-8(10)12-2;;/h9-10H,3-6H2,1-2H3;2*1H
CQBCVFHLZAVNPF-UHFFFAOYSA-N

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Applicazioni

Reactant for:
  • Synthesis of glutathione-sensitive cross-linked polyethylenimine gene vector
  • Preparation of cyclodextrin-containing polymers designed for gene delivery
  • Crosslinking of chick oviduct progesterone-receptor subunits

Avvertenza

The reagant is readily hydrolyzed at neutral pH. Avoid use of reducing agents during coupling reactions.

Altre note

Note that the amidine linkage preserves original primary amine positive charge. The disulfide linkage is cleavable by mild reduction. Incorporates an eight atom linker.

Pittogrammi

Exclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Skin Irrit. 2

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves


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