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246298

Sigma-Aldrich

4-Methoxyindole

99%

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About This Item

Formula empirica (notazione di Hill):
C9H9NO
Numero CAS:
4837-90-5
Peso molecolare:
147.17
Numero MDL:
MFCD00009737
Codice UNSPSC:
12352100
ID PubChem:
24854800
NACRES:
NA.22

Saggio

99%

Forma fisica

powder

P. eboll.

181-183 °C/24 mmHg (lit.)

Punto di fusione

69-70 °C (lit.)

Solubilità

ethanol: 50 mg/mL, clear, faintly yellow

Stringa SMILE

COc1cccc2[nH]ccc12

InChI

1S/C9H9NO/c1-11-9-4-2-3-8-7(9)5-6-10-8/h2-6,10H,1H3
LUNOXNMCFPFPMO-UHFFFAOYSA-N

Applicazioni

4-Methoxyindole was used for comparing the complexation reaction of β-cyclodextrin (β-CD) with pindolol using reversed-phase liquid chromatography.
Reactant for preparation of:
  • GABA analogs
  • Sodium-Dependent Glucose Co-transporter 2 (SGLT2) Inhibitors for the Management of Hyperglycemia in Diabetes
  • Anticancer agents
  • Integrase strand-transfer inhibitors (INSTIs)
  • Inhibitor of Proliferation of Colon Cancer Cells
  • Isomeridianin G as GSK-3ß inhibitors
  • HIV-1 integrase inhibitors
  • Inhibitors of mitogen activated protein kinase-activated protein kinase 2 (MK-2)

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H315,H319,H335

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Sigma-Aldrich

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Carmen Gazpio et al.
Journal of pharmaceutical and biomedical analysis, 37(3), 487-492 (2005-03-03)
The complexation with beta-cyclodextrin (beta-CD) has been investigated using reversed-phase liquid chromatography. The compounds tested have been pindolol and, for comparison purposes, indole and 4-methoxyindole. The retention behaviour has been analysed on a Kromasil 100 C18 column and the mobile
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Applied biochemistry and biotechnology, 181(4), 1590-1610 (2016-11-11)
The enantioselective epoxidation of styrene and related compounds by two-component styrene monooxygenases (SMOs) has targeted these enzymes for development as biocatalysts. In the present work, we prepare genetically engineered fusion proteins that join the C-terminus of the epoxidase (StyA) to
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International journal of pharmaceutics, 477(1-2), 96-101 (2014-10-15)
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Journal of pharmacokinetics and pharmacodynamics, 42(4), 401-408 (2015-07-04)
3,3'-Diindolylmethane (DIM) has been investigated as a potential anti-cancer chemopreventive agent in many preclinical and clinical studies. In this study, we sought to characterize the pharmacokinetics of DIM and to build a pharmacokinetic (PK) and pharmacodynamic (PD) model of the

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