Passa al contenuto
Merck

ZAK

Sinonimi:
AZK, MLK7, MLT, MLTK, MRK, mlklak, pk
Specie:
Human ZAK (51776), Mouse Zak (65964), Rat Zak (311743), chicken ZAK (424149), dog ZAK (478802), cow ZAK (519251)
ID UniProtKB:
ID gene:
  • Human(51776) Summary: This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
  • Mouse(65964) sterile alpha motif and leucine zipper containing kinase AZK
  • Rat(311743) sterile alpha motif and leucine zipper containing kinase AZK
  • chicken(424149) sterile alpha motif and leucine zipper containing kinase AZK
  • dog(478802) sterile alpha motif and leucine zipper containing kinase AZK
  • cow(519251) sterile alpha motif and leucine zipper containing kinase AZK

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
WH0051776M2
Monoclonal Anti-ZAK antibody produced in mouse, clone 3D11, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
immunofluorescence
western blot
SAB1409435
Monoclonal Anti-ZAK antibody produced in mouse, clone 2G7, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
immunofluorescence
western blot
SAB1409434
Monoclonal Anti-ZAK antibody produced in mouse, clone 3B6, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
immunofluorescence
western blot

Proteins

N° Catalogo
Descrizione
Specie
SRP5101
ZAK, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Specie
human