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Merck

TP53

tumor protein p53

Sinonimi:
BCC7, LFS1, P53, TRP53
Specie:
Human TP53 (7157), Rat Tp53 (24842), Zebrafish tp53 (30590), Horse TP53 (100062044), domestic cat TP53 (493847), dog TP53 (403869), chicken TP53 (396200), cow TP53 (281542), sheep TP53 (443421), domestic guinea pig Tp53 (100379269) ...Più
ID UniProtKB:
P04637, Q15086, Q15087, Q15088, Q16535, Q16807, Q16808, Q16809
ID gene:
  • Human(7157) Summary: This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013]
  • Rat(24842) tumor protein p53
  • Zebrafish(30590) tumor protein p53
  • Horse(100062044) tumor protein p53
  • domestic cat(493847) tumor protein p53
  • dog(403869) tumor protein p53
  • chicken(396200) tumor protein p53
  • cow(281542) tumor protein p53
  • sheep(443421) tumor protein p53
  • domestic guinea pig(100379269) tumor protein p53
  • Domestic Rabbit(100009292) tumor protein p53
  • naked mole-rat(101701769) tumor protein p53

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ELISA

N° Catalogo
Descrizione
Specie
RAB0500
Human p53 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Specie
human
RAB0910
Rat Tp53 / Cellular Tumor Antigen p53 ELISA Kit, ,
Specie
rat

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
MABE339
Anticorpo anti-p53 (wild-type), clone PAb1620, clone Pab1620, from mouse,
Reattività con
human, mouse
Applicazione
immunohistochemistry
western blot
453M-9
p53 (DO7) Mouse Monoclonal Antibody, ,
Reattività con
human
Applicazione
immunohistochemistry
SAB5702066
Anti-Acetyl-p53-K382 Antibody, clone 0, Rabbit Monoclonal, ,
Reattività con
mouse
Applicazione
CBL404
Anti-p53 Antibody, aa 211-220, clone240, clone PAb240, Chemicon®, from mouse,
Reattività con
bovine, chicken, hamster, human, monkey, mouse, rat
Applicazione
immunohistochemistry
immunoprecipitation (IP)
western blot
OP43
Anti-p53 (Ab-6) (Pantropic) Mouse mAb (DO-1), liquid, clone DO-1, Calbiochem®,
Reattività con
feline, human
Applicazione

Small Molecule - Inhibitor

N° Catalogo
Descrizione
Specie
PZ0115
CP-31398 dihydrochloride hydrate, ≥98% (HPLC),
Specie
mouse, rat, human

Proteins

N° Catalogo
Descrizione
Specie
23-034-M
p53 Protein, 10 µg, Full length, recombinant human p53. N-terminal c-Myc, 6His-tagged. For use in Enzyme Assays. Functions as a substrate in ubiquitination assays.,
Specie
14-865
p53-GST (recombinant protein), ,
Specie
P6249
p53 human, recombinant, expressed in E. coli, buffered aqueous glycerol solution,
Specie
human
P6374
p53 human, recombinant, expressed in baculovirus infected Sf21 cells,
Specie
human
SRP2108
p53 (1-81), mutant, GST tagged human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
EHU123221
MISSION® esiRNA, targeting human TP53,
Specie
human