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Merck

TNFRSF10C

tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain

Sinonimi:
CD263, DCR1, DCR1-TNFR, LIT, TRAIL-R3, TRAILR3, TRID
Specie:
ID UniProtKB:
ID gene:
  • Human(8794) Summary: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq, Jul 2008]

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ELISA

N° Catalogo
Descrizione
Specie
Human TRAIL R3 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Specie
human

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-DCR1 (ab1) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunocytochemistry

western blot
Monoclonal Anti-CD263, azide free antibody produced in mouse, clone TRAIL-R3-02, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
flow cytometry
Monoclonal Anti-CD263-PE antibody produced in mouse, clone TRAIL-R3-02, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
flow cytometry
Anti-DCR1 (ab2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunofluorescence

western blot
Monoclonal Anti-CD263-APC antibody produced in mouse, clone TRAIL-R3-02,
Reattività con
Applicazione
flow cytometry

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human TNFRSF10C,
Specie
human