Passa al contenuto
Merck

SKP1

S-phase kinase-associated protein 1

Sinonimi:
EMC19, OCP-II, OCP2, SKP1A, TCEB1L, p19A
Specie:
Human SKP1 (6500), Rat Skp1 (287280), Thale Cress SKP1 (843928), Zebrafish skp1 (393716), chicken SKP1 (416319), domestic cat SKP1 (101099017), dog SKP1 (474682), cow SKP1 (615427), Goat SKP1 (100861021), sheep SKP1 (100240716) ...Più
ID UniProtKB:
P63208, D3DQ97, D3DQ98, P34991, Q8TAY2
ID gene:
  • Human(6500) Summary: This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Jul 2008]
  • Rat(287280) S-phase kinase-associated protein 1
  • Thale Cress(843928) S-phase kinase-associated protein 1
  • Zebrafish(393716) S-phase kinase-associated protein 1
  • chicken(416319) S-phase kinase-associated protein 1
  • domestic cat(101099017) S-phase kinase-associated protein 1
  • dog(474682) S-phase kinase-associated protein 1
  • cow(615427) S-phase kinase-associated protein 1
  • Goat(100861021) S-phase kinase-associated protein 1
  • sheep(100240716) S-phase kinase-associated protein 1
  • domestic guinea pig(100135616) S-phase kinase-associated protein 1A
  • naked mole-rat(101704606) S-phase kinase-associated protein 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
MABS1229
Anti-SKP1 Antibody, clone 3F3.1, clone 3F3.1, from mouse,
Reattività con
human, mouse
Applicazione
immunocytochemistry
western blot
HPA058134
Anti-SKP1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunofluorescence
SAB5300376
Monoclonal Anti-SKP1 antibody produced in mouse, clone 4E11, ascites fluid,
Reattività con
human
Applicazione
ELISA
flow cytometry
immunofluorescence
immunohistochemistry
western blot
ST1709
Anti-SKP1A Mouse mAb (1H8), liquid, clone 1H8, Calbiochem®,
Reattività con
human
Applicazione
SAB1404372
Monoclonal Anti-SKP1A, (C-terminal) antibody produced in mouse, clone 2E6, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
immunofluorescence
western blot

Proteins

N° Catalogo
Descrizione
Specie
23-030-M
SCF-Fbw7 Protein Complex, Active, 10 µg, Active complex of four (4) full length, recombinant human enzymes: Fbw7, Skp1, Cul1 & Rbx1. For use in Enzyme Assays. Functions as an E3 ligase in ubiquitination assays.,
Specie
human
23-023-M
SCF-Skp2 Protein Complex, Active, 10 µg, Active complex of five (5) full length, recombinant human enzymes: Skp1, Skp2, Cul1, Rbx1 & Cks1. For use in Enzyme Assays. Functions as an E3 ligase in ubiquitination assays.,
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
EHU134251
MISSION® esiRNA, targeting human SKP1,
Specie
human