Passa al contenuto
Merck

OTX2

orthodenticle homeobox 2

Sinonimi:
CPHD6, MCOPS5
Specie:
Human OTX2 (5015), Mouse Otx2 (18424), Rat Otx2 (305858), Zebrafish otx2 (30501), cow OTX2 (538953), domestic cat OTX2 (101094107), chicken OTX2 (395191), dog OTX2 (490708), sheep OTX2 (101114527), domestic guinea pig Otx2 (100729098) ...Più
ID UniProtKB:
P32243, B2RAN5, Q6GTV3, Q9HAW3, Q9P2R1
ID gene:
  • Human(5015) Summary: This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine. [provided by RefSeq, Jul 2012]
  • Mouse(18424) orthodenticle homolog 2 (Drosophila)
  • Rat(305858) orthodenticle homeobox 2
  • Zebrafish(30501) orthodenticle homolog 2
  • cow(538953) orthodenticle homeobox 2
  • domestic cat(101094107) orthodenticle homeobox 2
  • chicken(395191) orthodenticle homeobox 2
  • dog(490708) orthodenticle homeobox 2
  • sheep(101114527) orthodenticle homeobox 2
  • domestic guinea pig(100729098) orthodenticle homeobox 2
  • naked mole-rat(101696878) orthodenticle homeobox 2
  • Domestic Rabbit(100009374) orthodenticle homeobox 2

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
HPA000633
Anti-OTX2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
AB9566-I
Anticorpo anti-OTX2, from rabbit, purified by affinity chromatography,
Reattività con
bovine, human, rat, rhesus macaque
Applicazione
immunohistochemistry
western blot
SAB5300043
Monoclonal Anti-OTX2 antibody produced in mouse, clone 1H12C4B5, ascites fluid,
Reattività con
human
Applicazione
ELISA
flow cytometry
immunofluorescence
immunohistochemistry
western blot
AV32439
Anti-OTX2 antibody produced in rabbit, affinity isolated antibody,
Reattività con
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat, sheep
Applicazione
immunohistochemistry
western blot
ZRB2940
Anti-OTX2 Antibody, clone 1O4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
xenopus, bovine, horse, human, monkey, porcine, rat
Applicazione
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot

esiRNA

N° Catalogo
Descrizione
Specie
EHU129881
MISSION® esiRNA, targeting human OTX2,
Specie
human
EMU062301
MISSION® esiRNA, targeting mouse Otx2,
Specie
mouse