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Merck

NPR2

natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)

Sinonimi:
AMDM, ANPRB, ANPb, GUC2B, GUCY2B, NPRB, NPRBi
Specie:
ID UniProtKB:
ID gene:
  • Human(4882) Summary: This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type. [provided by RefSeq, Jul 2008]
  • Mouse(230103) natriuretic peptide receptor 2
  • Rat(116564) natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
  • chicken(100859339) natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
  • dog(474762) natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
  • Horse(100055416) natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
  • cow(281357) natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
  • domestic cat(101094301) natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
  • Goat(100861577) natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
  • sheep(101112950) natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
  • naked mole-rat(101712380) natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
  • domestic guinea pig(100732021) natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)

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Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Monoclonal Anti-NPR2 antibody produced in mouse, clone 2A6, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
immunohistochemistry

western blot
Monoclonal Anti-NPR2 antibody produced in mouse, clone 3D6, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting mouse Npr2,
Specie
mouse
MISSION® esiRNA, targeting human NPR2,
Specie
human