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Merck

NOD1

nucleotide-binding oligomerization domain containing 1

Sinonimi:
CARD4, CLR7.1, NLRC1
Specie:
ID UniProtKB:
ID gene:
  • Human(10392) Summary: This gene encodes a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid. Multiple alternatively spliced transcript variants differring in the 5' UTR have been described, but the full-length nature of these variants has not been determined. [provided by RefSeq, Oct 2009]
  • Mouse(107607) nucleotide-binding oligomerization domain containing 1
  • Rat(500133) nucleotide-binding oligomerization domain containing 1
  • Zebrafish(100330810) nucleotide-binding oligomerization domain containing 1
  • Horse(100069844) nucleotide-binding oligomerization domain containing 1
  • cow(781426) nucleotide-binding oligomerization domain containing 1
  • domestic cat(101086963) nucleotide-binding oligomerization domain containing 1
  • chicken(420677) nucleotide-binding oligomerization domain containing 1
  • dog(482382) nucleotide-binding oligomerization domain containing 1
  • sheep(101102721) nucleotide-binding oligomerization domain containing 1
  • naked mole-rat(101724724) nucleotide-binding oligomerization domain containing 1
  • Domestic Rabbit(100345423) nucleotide-binding oligomerization domain containing 1
  • domestic guinea pig(100722894) nucleotide-binding oligomerization domain containing 1

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Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-NOD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunofluorescence
Monoclonal Anti-NOD1, (N-terminal) antibody produced in mouse, clone 3F10, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
western blot
Anti-NOD1 (C-terminal) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reattività con
bovine, canine, human, mouse, rat
Applicazione
ELISA
western blot
Anti-NOD1/CARD4 Antibody, clone 021, clone 021, 1 mg/mL, from mouse,
Reattività con
human
Applicazione
flow cytometry
western blot

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting mouse Nod1,
Specie
mouse