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Merck

KCNQ1

potassium voltage-gated channel, KQT-like subfamily, member 1

Sinonimi:
ATFB1, ATFB3, JLNS1, KCNA8, KCNA9, KVLQT1, Kv1.9, Kv7.1, LQT, LQT1, RWS, SQT2, WRS
Specie:
ID UniProtKB:
ID gene:
  • Human(3784) Summary: This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome), Jervell and Lange-Nielsen syndrome, and familial atrial fibrillation. This gene exhibits tissue-specific imprinting, with preferential expression from the maternal allele in some tissues, and biallelic expression in others. This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS), and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2011]
  • Mouse(16535) potassium voltage-gated channel, subfamily Q, member 1
  • Rat(84020) potassium voltage-gated channel, KQT-like subfamily, member 1
  • Zebrafish(557498) potassium voltage-gated channel, KQT-like subfamily, member 1
  • chicken(423090) potassium voltage-gated channel, KQT-like subfamily, member 1
  • cow(784876) potassium voltage-gated channel, KQT-like subfamily, member 1
  • Horse(100034129) potassium voltage-gated channel, KQT-like subfamily, member 1
  • domestic cat(101092644) potassium voltage-gated channel, KQT-like subfamily, member 1
  • dog(483669) potassium voltage-gated channel, KQT-like subfamily, member 1
  • domestic guinea pig(100379230) potassium voltage-gated channel, subfamily Q, member 1
  • naked mole-rat(101725681) potassium voltage-gated channel, KQT-like subfamily, member 1
  • sheep(101119596) potassium voltage-gated channel, KQT-like subfamily, member 1

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Antibodies

Product Number
Descrizione
Reattività con
Applicazione
Anti-Kcnq1 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
Anti-KCNQ1 (C-terminal) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunohistochemistry

western blot
Anti-Potassium Channel KvLQT1 Antibody, CT, Chemicon®, from rabbit,
Reattività con
human, mouse, rat
Applicazione
immunohistochemistry
western blot
Anti-KCNQ1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
Anti-KCNQ1, affinity isolated antibody,
Reattività con
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Applicazione
immunohistochemistry
western blot

Small Molecule - Blocker

Product Number
Descrizione
Specie
Retigabine, analytical standard,
Specie
human
Guanidina, Molecular Biology, ≥99%,
Specie
human
Guanidina, ≥98%,
Specie
human
Guanidina, ≥99% (titration), organic base and chaeotropic agent,
Specie
human
Guanidina, ,
Specie
human

esiRNA

Product Number
Descrizione
Specie
MISSION® esiRNA, targeting human KCNQ1,
Specie
human
MISSION® esiRNA, targeting mouse Kcnq1,
Specie
mouse