Passa al contenuto
Merck

HP

haptoglobin

Sinonimi:
BP, HP2ALPHA2, HPA1S
Specie:
ID UniProtKB:
ID gene:
  • Human(3240) Summary: This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(15439) haptoglobin
  • Rat(24464) haptoglobin
  • Zebrafish(566096) haptoglobin
  • fruit fly(251278) humped
  • dog(479668) haptoglobin
  • cow(280692) haptoglobin
  • domestic cat(100144610) haptoglobin
  • domestic guinea pig(100721435) haptoglobin
  • naked mole-rat(101705743) haptoglobin
  • sheep(101102413) haptoglobin
  • Domestic Rabbit(100008816) haptoglobin

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-Haptoglobin antibody produced in rabbit, IgG fraction of antiserum, lyophilized powder,
Reattività con
human
Applicazione
ELISA
Anti-Haptoglobin antibody, Mouse monoclonal, clone HG-36, purified from hybridoma cell culture,
Reattività con
human
Applicazione
ELISA
dot blot

immunoprecipitation (IP)

western blot
Anti-Haptoglobin (HP) antibody produced in rabbit, ,
Reattività con
human, mouse, rat
Applicazione
immunohistochemistry
western blot
Monoclonal Anti-Haptoglobin antibody produced in mouse, clone HG-36, ascites fluid,
Reattività con
human
Applicazione
ELISA
Anti-Hp Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione

Proteins

N° Catalogo
Descrizione
Specie
Haptoglobin from pooled human plasma, ≥95% (SDS-PAGE), lyophilized powder,
Specie
human
Haptoglobin Human, Phenotype 1-1, 98-100%, essentially salt-free, lyophilized powder,
Specie
human
Haptoglobin (Phenotype 1-1) from human plasma, ≥95% (SDS-PAGE),
Specie
human
Haptoglobin Plasma (MixedType) from human plasma, ≥95% (SDS-PAGE),
Specie
human
Haptoglobin (Phenotype 2-2) from human plasma, ≥95% (SDS-PAGE),
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human HP,
Specie
human