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Merck

HHIP

hedgehog interacting protein

Sinonimi:
HIP
Specie:
ID UniProtKB:
ID gene:
  • Human(64399) Summary: This gene encodes a member of the hedgehog-interacting protein (HHIP) family. The hedgehog (HH) proteins are evolutionarily conserved protein, which are important morphogens for a wide range of developmental processes, including anteroposterior patterns of limbs and regulation of left-right asymmetry in embryonic development. Multiple cell-surface receptors are responsible for transducing and/or regulating HH signals. The HHIP encoded by this gene is a highly conserved, vertebrate-specific inhibitor of HH signaling. It interacts with all three HH family members, SHH, IHH and DHH. Two single nucleotide polymorphisms (SNPs) near this gene are significantly associated with risk of chronic obstructive pulmonary disease (COPD). A single nucleotide polymorphism in this gene is also strongly associated with human height.[provided by RefSeq, Feb 2011]
  • Mouse(15245) Hedgehog-interacting protein
  • Rat(291936) Hedgehog-interacting protein
  • sheep(101111396) hedgehog interacting protein
  • Domestic Rabbit(100344588) hedgehog interacting protein
  • domestic guinea pig(100728644) hedgehog interacting protein
  • naked mole-rat(101724427) hedgehog interacting protein
  • Zebrafish(326102) hedgehog interacting protein
  • domestic cat(101087058) hedgehog interacting protein
  • cow(540830) hedgehog interacting protein
  • Horse(100062868) hedgehog interacting protein
  • dog(475452) hedgehog interacting protein
  • chicken(422460) hedgehog interacting protein

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Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Monoclonal Anti-HHIP antibody produced in mouse, clone 5D11, purified immunoglobulin, buffered aqueous solution,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-HHIP antibody produced in rabbit, ,
Reattività con
chicken, human, mouse
Applicazione
immunocytochemistry
immunofluorescence

immunohistochemistry

western blot

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting mouse Hhip,
Specie
mouse
MISSION® esiRNA, targeting human HHIP,
Specie
human