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Merck

HCN4

hyperpolarization activated cyclic nucleotide-gated potassium channel 4

Sinonimi:
SSS2
Specie:
ID UniProtKB:
ID gene:
  • Human(10021) Summary: This gene encodes a member of the hyperpolarization-activated cyclic nucleotide-gated potassium channels. The encoded protein shows slow kinetics of activation and inactivation, and is necessary for the cardiac pacemaking process. This channel may also mediate responses to sour stimuli. Mutations in this gene have been linked to sick sinus syndrome 2, also known as atrial fibrillation with bradyarrhythmia or familial sinus bradycardia. Two pseudogenes have been identified on chromosome 15. [provided by RefSeq, Oct 2008]
  • Mouse(330953) hyperpolarization-activated, cyclic nucleotide-gated K+ 4
  • Rat(59266) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
  • domestic guinea pig(100717049) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
  • naked mole-rat(101715130) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
  • sheep(101117337) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
  • Domestic Rabbit(100009452) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
  • Zebrafish(557843) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
  • cow(785689) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
  • domestic cat(101090363) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
  • dog(448794) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
  • chicken(427478) hyperpolarization activated cyclic nucleotide-gated potassium channel 4

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Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-HCN4 Antibody, Chemicon®, from rabbit,
Reattività con
human, mouse, rat
Applicazione
immunohistochemistry
western blot
Anti-HCN4 Antibody, clone PG2-1A4, clone PG2-1A4, from rat,
Reattività con
mouse
Applicazione
electron microscopy
immunofluorescence

immunohistochemistry

western blot
Monoclonal Anti-HCN4 antibody produced in mouse, clone S114-10, 1 mg/mL, purified immunoglobulin,
Reattività con
human, mouse, rat
Applicazione
immunocytochemistry
immunohistochemistry

western blot
Anti-HCN4, affinity isolated antibody,
Reattività con
human
Applicazione
immunohistochemistry
Anti-HCN4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry

Small Molecule - Blocker

N° Catalogo
Descrizione
Specie
Ivabradine hydrochloride, ≥98% (HPLC),
Specie
human
Dronedarone hydrochloride, ≥98% (HPLC),
Specie
human
Dronedarone hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Specie
human
Dronedarone hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Specie
human