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Merck

GZMB

granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)

Sinonimi:
CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT
Specie:
Human GZMB (3002), Mouse Gzmb (14939), Rat Gzmb (171528), dog GZMB (490630), cow GZMB (508646), cow GZMB (281731), Horse GZMB (100033978), domestic cat GZMB (100127106), domestic guinea pig Gzmb (100736180), naked mole-rat Gzmb (101702156)
ID UniProtKB:
P10144, Q8N1D2, Q9UCC1
ID gene:
  • Human(3002) Summary: Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response. [provided by RefSeq, Jul 2008]
  • Mouse(14939) granzyme B
  • Rat(171528) granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
  • dog(490630) granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
  • cow(508646) granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
  • cow(281731) granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
  • Horse(100033978) granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
  • domestic cat(100127106) granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
  • domestic guinea pig(100736180) granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
  • naked mole-rat(101702156) granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)

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ELISA

N° Catalogo
Descrizione
Specie
RAB0210
Mouse Granzyme B ELISA Kit, for serum, plasma and cell culture supernatant,
Specie
mouse
RAB1498
Human Granzyme B ELISA, for serum, plasma and cell culture supernatants,
Specie
human

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
262A-1
Granzyme B Rabbit Polyclonal Antibody, ,
Reattività con
human
Applicazione
immunohistochemistry
262R-1
Granzyme B (EP230) Rabbit Monoclonal Primary Antibody, ,
Reattività con
human
Applicazione
immunohistochemistry
MAB3070
Anti-Granzyme B Antibody, clone GrB-7, culture supernatant, clone GrB-7, Chemicon®,
Reattività con
human
Applicazione
immunohistochemistry
western blot
ZRB2736
Anti-Granzyme B Antibody, clone 3M4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
human
Applicazione
ELISA
affinity binding assay
flow cytometry
western blot
HPA003418
Anti-GZMB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
western blot

Proteins

N° Catalogo
Descrizione
Specie
SRE0021
Granzyme B human, recombinant, expressed in insect cells, ≥90% (SDS-PAGE),
Specie
human
SRP3202
Granzyme B from mouse, recombinant, expressed in Hi-5 Insect cells, ≥97% (SDS-PAGE), ≥97% (HPLC), suitable for cell culture,
Specie
mouse

esiRNA

N° Catalogo
Descrizione
Specie
EHU106641
MISSION® esiRNA, targeting human GZMB,
Specie
human

Small Molecule - Substrate

N° Catalogo
Descrizione
Specie
A6470
N-Acetyl-Ile-Glu-Pro-Asp-p-nitroanilide, ≥97% (HPLC), powder,
Specie
rat, mouse, human
A9968
N-Acetyl-Ile-Glu-Thr-Asp-p-nitroanilide, ≥95%,
Specie
rat, mouse, human
A6220
N-Acetyl-Ile-Glu-Pro-Asp-7-amido-4-methylcoumarin, ≥97% (HPLC), powder,
Specie
rat, mouse, human
A4188
N-Acetyl-Ile-Glu-Thr-Asp-7-Amido-4-methylcoumarin, ≥97% (HPLC), powder,
Specie
rat, mouse, human