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Merck

GSTA4

glutathione S-transferase alpha 4

Sinonimi:
GSTA4-4, GTA4
Specie:
ID UniProtKB:
ID gene:
  • Human(2941) Summary: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, which are located in a cluster on chromosome 6, are highly related and encode enzymes with glutathione peroxidase activity that function in the detoxification of lipid peroxidation products. Reactive electrophiles produced by oxidative metabolism have been linked to a number of degenerative diseases including Parkinson's disease, Alzheimer's disease, cataract formation, and atherosclerosis. [provided by RefSeq, Jul 2008]
  • Mouse(14860) glutathione S-transferase, alpha 4
  • Rat(300850) glutathione S-transferase alpha 4
  • domestic guinea pig(100732190) glutathione S-transferase alpha 4
  • naked mole-rat(101714626) glutathione S-transferase alpha 4
  • cow(533917) glutathione S-transferase alpha 4
  • Horse(100056597) glutathione S-transferase alpha 4
  • dog(474939) glutathione S-transferase alpha 4

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Activity Assay

N° Catalogo
Descrizione
Specie
Glutathione Assay Kit, Fluorimetric, sufficient for 200 multiwell tests,
Specie
human
Glutathione-S-Transferase (GST) Assay Kit, sufficient for 500 multiwell tests,
Specie
human

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-GSTA4 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reattività con
human, mouse
Applicazione
western blot
Anti-GSTA4 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
western blot

Cell Lines

N° Catalogo
Descrizione
Specie
GST A4-4, Recombinant Human, ,
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting mouse Gsta4,
Specie
mouse
MISSION® esiRNA, targeting human GSTA4,
Specie
human