DPYD
dihydropyrimidine dehydrogenase
Sinonimi:
DHP, DHPDHASE, DPD
Specie:
Human DPYD (1806), Mouse Dpyd (99586), Rat Dpyd (81656), sheep DPYD (101109311), domestic guinea pig Dpyd (100727906), naked mole-rat Dpyd (101704452), chicken DPYD (429083), cow DPYD (281124), Horse DPYD (100057177), domestic cat DPYD (101084380)
ID UniProtKB:
ID gene:
- Human(1806) Summary: The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
- Mouse(99586) dihydropyrimidine dehydrogenase
- Rat(81656) dihydropyrimidine dehydrogenase
- sheep(101109311) dihydropyrimidine dehydrogenase
- domestic guinea pig(100727906) dihydropyrimidine dehydrogenase
- naked mole-rat(101704452) dihydropyrimidine dehydrogenase
- chicken(429083) dihydropyrimidine dehydrogenase
- cow(281124) dihydropyrimidine dehydrogenase
- Horse(100057177) dihydropyrimidine dehydrogenase
- domestic cat(101084380) dihydropyrimidine dehydrogenase
- dog(479935) dihydropyrimidine dehydrogenase
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-Dihydropyrimidine dehydrogenase/DPYD Antibody, from rabbit, purified by affinity chromatography,
Reattività con
bovine, horse, human, porcine, primate
Applicazione
immunohistochemistry
western blot
western blot
Anti-DPYD antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
immunohistochemistry
western blot
western blot
esiRNA
N° Catalogo
Descrizione
Specie