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Merck

DNMT3A

DNA (cytosine-5-)-methyltransferase 3 alpha

Sinonimi:
DNMT3A2, M.HsaIIIA
Specie:
ID UniProtKB:
ID gene:
  • Human(1788) Summary: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(13435) DNA methyltransferase 3A
  • Rat(444984) DNA (cytosine-5-)-methyltransferase 3 alpha
  • chicken(421991) DNA (cytosine-5-)-methyltransferase 3 alpha
  • dog(482996) DNA (cytosine-5-)-methyltransferase 3 alpha
  • domestic cat(100510798) DNA (cytosine-5-)-methyltransferase 3 alpha
  • cow(359716) DNA (cytosine-5-)-methyltransferase 3 alpha
  • Horse(100055881) DNA (cytosine-5-)-methyltransferase 3 alpha
  • sheep(100500776) DNA (cytosine-5-)-methyltransferase 3 alpha
  • Domestic Rabbit(100344715) DNA (cytosine-5-)-methyltransferase 3 alpha
  • domestic guinea pig(100721625) DNA (cytosine-5-)-methyltransferase 3 alpha
  • naked mole-rat(101718745) DNA (cytosine-5-)-methyltransferase 3 alpha

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Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-DNMT3A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human, mouse, rat
Applicazione
immunofluorescence
immunohistochemistry
Anti-DNMT3A antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reattività con
bovine, human, mouse, rat
Applicazione
ELISA
western blot
Anti-DNMT3A2 Antibody, from rabbit,
Reattività con
human
Applicazione
ELISA
immunocytochemistry

western blot
Anti- DNMT3A antibody produced in rabbit, ,
Reattività con
human, mouse, rat
Applicazione
immunohistochemistry
western blot
Anti-DNMT3A antibody produced in rabbit, ,
Reattività con
human, mouse, rat
Applicazione
immunofluorescence
western blot

Small Molecule - Inhibitor

N° Catalogo
Descrizione
Specie
5-Aza-2′-deoxycytidine, ≥97%,
Specie
human
Azacitidina, United States Pharmacopeia (USP) Reference Standard,
Specie
human
5-azacitidina, Hybri-Max, γ-irradiated, lyophilized powder, BioXtra, suitable for hybridoma,
Specie
human
5-azacitidina, Pharmaceutical Secondary Standard; Certified Reference Material,
Specie
human
5-azacitidina, ≥98% (HPLC),
Specie
human

Proteins

N° Catalogo
Descrizione
Specie
DNMT3a Active human, recombinant, expressed in baculovirus infected insect cells,
Specie
human
DNMT3A/DNMT3L active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥90% (SDS-PAGE),
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human DNMT3A,
Specie
human
MISSION® esiRNA, targeting mouse Dnmt3a,
Specie
mouse