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Merck

DDR2

discoidin domain receptor tyrosine kinase 2

Sinonimi:
MIG20a, NTRKR3, TKT, TYRO10
Specie:
ID UniProtKB:
ID gene:
  • Human(4921) Summary: Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
  • Mouse(18214) discoidin domain receptor family, member 2
  • Rat(685781) discoidin domain receptor tyrosine kinase 2
  • Zebrafish(559428) discoidin domain receptor family, member 2
  • dog(478987) discoidin domain receptor tyrosine kinase 2
  • chicken(396404) discoidin domain receptor tyrosine kinase 2
  • Horse(100058300) discoidin domain receptor tyrosine kinase 2
  • cow(533523) discoidin domain receptor tyrosine kinase 2
  • domestic cat(101085267) discoidin domain receptor tyrosine kinase 2
  • sheep(101109754) discoidin domain receptor tyrosine kinase 2
  • naked mole-rat(101712349) discoidin domain receptor tyrosine kinase 2
  • domestic guinea pig(100729537) discoidin domain receptor tyrosine kinase 2

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ELISA

N° Catalogo
Descrizione
Specie
Phosphotyrosine DDR2 / Discoidin domain-containing Receptor 2 ELISA Kit, ,
Specie
human

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-DDR2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunofluorescence
Anti-DDR2 Antibody, clone 1M8U7, Rabbit Monoclonal, ,
Reattività con
human, rat
Applicazione
western blot
Monoclonal Anti-DDR2 antibody produced in mouse, clone 3B11E4, ascites fluid,
Reattività con
human
Applicazione
ELISA
immunofluorescence

immunohistochemistry

western blot
MONOCLONAL ANTI-DDR2 antibody produced in mouse, clone 484CT5.5.4, crude ascites, buffered aqueous solution,
Reattività con
human
Applicazione
western blot

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting mouse Ddr2,
Specie
mouse
MISSION® esiRNA, targeting human DDR2,
Specie
human
MISSION® esiRNA, targeting mouse Ddr2,
Specie
mouse