CYBB
cytochrome b-245, beta polypeptide
Sinonimi:
AMCBX2, CGD, GP91-1, GP91-PHOX, GP91PHOX, NOX2, p91-PHOX
Specie:
Human CYBB (1536), Mouse Cybb (13058), Rat Cybb (66021), Zebrafish cybb (393386), chicken CYBB (418581), cow CYBB (281112), dog CYBB (491825), sheep CYBB (100036757), Domestic Rabbit CYBB (100008801)
ID UniProtKB:
ID gene:
- Human(1536) Summary: Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. [provided by RefSeq, Jul 2008]
- Mouse(13058) cytochrome b-245, beta polypeptide
- Rat(66021) cytochrome b-245, beta polypeptide
- Zebrafish(393386) cytochrome b-245, beta polypeptide (chronic granulomatous disease)
- chicken(418581) cytochrome b-245, beta polypeptide
- cow(281112) cytochrome b-245, beta polypeptide
- dog(491825) cytochrome b-245, beta polypeptide (chronic granulomatous disease)
- sheep(100036757) cytochrome b-245, beta polypeptide
- Domestic Rabbit(100008801) cytochrome b-245 beta polypeptide
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Antibodies
N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-CYBB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
western blot
western blot
Anti-CYBB antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rabbit, rat
Applicazione
western blot
Anti-gp91phox (NOX2) Antibody, ,
Reattività con
human
Applicazione
flow cytometry
inhibition assay
western blot
inhibition assay
western blot
esiRNA
N° Catalogo
Descrizione
Specie