CDK2
cyclin-dependent kinase 2
Sinonimi:
p33(CDK2)
Specie:
Human CDK2 (1017), Mouse Cdk2 (12566), Rat Cdk2 (362817), Zebrafish cdk2 (406715), cow CDK2 (519217), chicken CDK2 (100529062), dog CDK2 (606931), domestic cat CDK2 (101093368), domestic guinea pig Cdk2 (100714324), naked mole-rat Cdk2 (101725353) ...Più
ID UniProtKB:
ID gene:
- Human(1017) Summary: The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported. [provided by RefSeq, Jul 2008]
- Mouse(12566) cyclin-dependent kinase 2
- Rat(362817) cyclin dependent kinase 2
- Zebrafish(406715) cyclin-dependent kinase 2
- cow(519217) cyclin-dependent kinase 2
- chicken(100529062) cyclin-dependent kinase 2
- dog(606931) cyclin-dependent kinase 2
- domestic cat(101093368) cyclin-dependent kinase 2
- domestic guinea pig(100714324) cyclin-dependent kinase 2
- naked mole-rat(101725353) cyclin-dependent kinase 2
- Goat(100860751) cyclin-dependent kinase 2
- sheep(100216433) cyclin-dependent kinase 2
- Domestic Rabbit(100134865) cyclin-dependent kinase 2
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Antibodies
N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-phospho-CDK2 (pThr160) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-phospho-CDK2 (pThr160) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
immunohistochemistry
western blot
western blot
Anti-CDK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunofluorescence
Anti-phospho-CDK1/CDC2 (pThr14) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
western blot
Anti-Phospho-CDK2-T160 antibody produced in rabbit, ,
Reattività con
human, mouse, rat
Applicazione
immunohistochemistry
western blot
western blot
Small Molecule - Inhibitor
Proteins
N° Catalogo
Descrizione
Specie
p27 Protein complex, activated, 10 µg, Activated complex of three (3) full length, recombinant human proteins: p27, Cyclin E1, & CDK2. Phosphorylated in vitro using CDK2/Cyclin E1. For use in Enzyme Assays. Behaves as a substrate in ubiquitin assays.,
Specie
human
Cdk1/cyclin B Protein, active, 10 µg, Active, C-terminal His6-tagged human full length Cdk1 & N-terminal GST-tagged human full length Cyclin B, for use in Kinase Assays.,
Specie
human
Cdk2/Cyclin E Protein, active, 10 µg, Active complex of recombinant full length human Cdk2 containing a C-terminal His6-tag & recombinant full-length human Cyclin E containing an N-terminal GST-tag. For use in Kinase Assays.,
Specie
human
CDK2/Cyclin A2, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Specie
human
CDK2/CyclinA1, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Specie
human
