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Merck

CCNH

cyclin H

Sinonimi:
CAK, p34, p37
Specie:
ID UniProtKB:
ID gene:
  • Human(902) Summary: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. A pseudogene of this gene is found on chromosome 4. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Nov 2010]
  • Mouse(66671) cyclin H
  • Rat(84389) cyclin H
  • domestic guinea pig(100726162) cyclin H
  • naked mole-rat(101714118) cyclin H
  • sheep(101104905) cyclin H
  • Zebrafish(541325) cyclin H
  • cow(615512) cyclin H
  • Horse(100065185) cyclin H
  • domestic cat(101095398) cyclin H
  • dog(479156) cyclin H
  • chicken(427328) cyclin H

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Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-CCNH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunofluorescence
Anti-phospho-Cyclin H (pThr315) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
western blot
Anti-Cyclin H Antibody, clone 3N5S3, Rabbit Monoclonal, ,
Reattività con
mouse
Applicazione
immunofluorescence
immunohistochemistry

western blot
Anti-CCNH antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
immunofluorescence
western blot

Proteins

N° Catalogo
Descrizione
Specie
CDK7/Cyclin H1/MNAT1, active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting mouse Ccnh,
Specie
mouse
MISSION® esiRNA, targeting human CCNH,
Specie
human