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Merck

CBX3

chromobox homolog 3

Sinonimi:
HECH, HP1-GAMMA, HP1Hs-gamma
Specie:
ID UniProtKB:
ID gene:
  • Human(11335) Summary: At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.[provided by RefSeq, Mar 2011]
  • Mouse(12417) chromobox 3
  • Rat(297093) chromobox homolog 3
  • naked mole-rat(101714000) chromobox homolog 3
  • domestic guinea pig(100714020) chromobox homolog 3
  • sheep(101106931) chromobox homolog 3
  • chicken(395355) chromobox homolog 3
  • dog(482015) chromobox homolog 3
  • cow(539788) chromobox homolog 3
  • domestic cat(101099363) chromobox homolog 3

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Antibodies

Product Number
Descrizione
Reattività con
Applicazione
Anticorpo anti-HP1γ, clone 42s2, clone 42s2, Upstate®, from mouse,
Reattività con
human, mouse
Applicazione
ChIP
immunohistochemistry

western blot
Anti-CBX3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry

western blot
Rabbit anti-CBX3 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Reattività con
human
Applicazione
immunohistochemistry
immunoprecipitation (IP)
Anti-HP1 gamma/CBX3 antibody produced in rabbit, ,
Reattività con
human, mouse, rat
Applicazione
immunohistochemistry
western blot
Anti-phospho-HP1 γ (Ser83) Antibody, Upstate®, from rabbit,
Reattività con
human
Applicazione
western blot

esiRNA

Product Number
Descrizione
Specie
MISSION® esiRNA, targeting human CBX3,
Specie
human
MISSION® esiRNA, targeting mouse Ensmusg00000059647,
Specie
mouse
MISSION® esiRNA, targeting mouse Cbx3,
Specie
mouse
MISSION® esiRNA, targeting mouse CBX3-PS2, CBX3-PS5,
Specie
mouse