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Merck

CASP14

caspase 14, apoptosis-related cysteine peptidase

Sinonimi:
Specie:
ID UniProtKB:
ID gene:
  • Human(23581) Summary: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier. [provided by RefSeq, Jul 2008]
  • Mouse(12365) caspase 14
  • Rat(299587) caspase 14
  • naked mole-rat(101720095) caspase 14, apoptosis-related cysteine peptidase
  • domestic guinea pig(100715745) caspase 14, apoptosis-related cysteine peptidase
  • sheep(101120827) caspase 14, apoptosis-related cysteine peptidase
  • chicken(776274) caspase 14, apoptosis-related cysteine peptidase
  • cow(517658) caspase 14, apoptosis-related cysteine peptidase
  • domestic cat(101099027) caspase 14, apoptosis-related cysteine peptidase
  • dog(610460) caspase 14, apoptosis-related cysteine peptidase

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Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-CASP14 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
Anti-Caspase-14 Antibody, from rabbit, purified by affinity chromatography,
Reattività con
human
Applicazione
immunohistochemistry
western blot
Monoclonal Anti-CASP14 antibody produced in mouse, clone 4C9, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
immunofluorescence

western blot
Anti-Caspase-14 Antibody, clone 6E2C1, Rabbit Monoclonal, ,
Reattività con
human, rat
Applicazione
western blot

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human CASP14,
Specie
human
MISSION® esiRNA, targeting mouse Casp14,
Specie
mouse