Passa al contenuto
Merck

AKR1C4

aldo-keto reductase family 1, member C4

Sinonimi:
3-alpha-HSD, C11, CDR, CHDR, DD-4, DD4, HAKRA
Specie:
ID UniProtKB:
ID gene:
  • Human(1109) Summary: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq, Jul 2008]
  • cow(282138) aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-AKR1C4 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
western blot
Anti-AKR1C4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
western blot
Anti-AKR1C4 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
western blot

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human AKR1C4,
Specie
human