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Merck

AANAT

aralkylamine N-acetyltransferase

Sinonimi:
DSPS, SNAT
Specie:
ID UniProtKB:
ID gene:
  • Human(15) Summary: The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
  • Mouse(11298) arylalkylamine N-acetyltransferase
  • Rat(25120) aralkylamine N-acetyltransferase
  • naked mole-rat(101713893) aralkylamine N-acetyltransferase
  • domestic guinea pig(100724241) aralkylamine N-acetyltransferase
  • Goat(100860947) aralkylamine N-acetyltransferase
  • sheep(443531) aralkylamine N-acetyltransferase
  • chicken(396066) aralkylamine N-acetyltransferase
  • dog(483331) aralkylamine N-acetyltransferase
  • domestic cat(101098178) aralkylamine N-acetyltransferase
  • cow(281583) arylalkylamine N-acetyltransferase

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Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-AANAT Antibody, serum, Chemicon®,
Reattività con
bovine, fish, human, rat, sheep
Applicazione
western blot
ANTI-AANAT (N-TERM) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Reattività con
human
Applicazione
western blot
Anti-AANAT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunofluorescence
Anti-phospho-Serotonin N-Acetyltransferase (N-Terminal) (pThr29) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reattività con
rat
Applicazione
western blot
Anti-Serotonin N-Acetyltransferase (C-Terminal) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reattività con
mouse, rat
Applicazione
western blot