Cytokines, chemokines, and growth factors are key mediators of immune system functions capable of signaling through autocrine, paracrine, and endocrine mechanisms. Their pleiotropic immunomodulatory properties allow these biomolecules to react to diverse stimuli and regulate the immune response, either promoting or inhibiting inflammation.

MILLIPLEX^® Human Cytokine/Chemokine/Growth Factor Panel A and Panel B

The open-architecture xMAP^® technology of the MILLIPLEX^® Human Cytokine/Chemokine/Growth Factor Panel A and Panel B enables multiplexing of many types of bioassays reducing time, labor, and costs over traditional methods. The capability of adding multiple conjugated beads to each sample results in the ability to obtain multiple cytokine results from each sample.

MILLIPLEX^® Human Cytokine Panel A and B offer you:

• The ability to select a 38-plex or 48-plex premixed kit
  
• The flexibility to choose any combination of analytes from our panel of 48 analytes to design a custom kit that better meets your needs
• A convenient “all-in-one” box format that provides all the necessary reagents you need to run your assay
• Small sample volume requirements (25 μL/well)
• Superior performance with rigorous assay development and quality control testing

Panel Details

These panels are 48-plex kits to be used for the simultaneous quantification of any or all of the following analytes in serum or plasma samples and tissue/cell lysate and culture supernatant samples:

• MILLIPLEX^® Human Cytokine/Chemokine/Growth Factor Panel A: sCD40L, EGF, Eotaxin, FGF-2, FLT-3L, Fractalkine, G-CSF, GM-CSF, GROα, IFNα2, IFNγ, IL-1α, IL-1β, IL-1RA, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-12 (p40), IL-12 (p70), IL-13, IL-15, IL-17A, IL-17E/IL-25, IL-17F, IL-18, IL-22, IL-27, IP-10, MCP-1, MCP-3, M-CSF, MDC, MIG, MIP-1α, MIP-1β, PDGF-AA, PDGF-AB/BB, RANTES*, TGFα, TNFα, TNFβ, VEGF-A
  
• MILLIPLEX^® Human Cytokine/Chemokine/Growth Factor Panel B: 6Ckine, sCD137, sFAS, sFASL, APRIL, BAFF, BCA-1, CCL28, CTACK, CXCL16, ENA-78, Eotaxin-2, Eotaxin-3, GCP-2, Granzyme A, Granzyme B, HMGB1, I-309, IFNβ, IFNω, IL-11, IL-16, IL-20, IL-21, IL-23, IL-24, IL-28A, IL-29, IL-31, IL-33, IL-34, IL-35, I-TAC, LIF, Lymphotactin, MCP-2, MCP-4, MIP-1δ, MIP-3α, MIP-3β, MPIF-1, Perforin, SCF, SDF-1, TARC, TPO, TRAIL, TSLP

* RANTES is always provided as a separate bead vial due to different dilution requirements for serum/ plasma samples. If measuring RANTES in serum/plasma, it is recommended to use a singleplex kit including RANTES only.

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