- New multicomponent approach for the synthesis of benzo[c]coumarin derivatives over MgO under solvent-free conditions.
New multicomponent approach for the synthesis of benzo[c]coumarin derivatives over MgO under solvent-free conditions.
Molecular diversity (2010-07-24)
Hassan Valizadeh, Ashraf Fakhari
PMID20652403
ABSTRACT
In this study, a three-component one-pot synthesis of select 5-amino-6-cyano-3-hydroxybenzo[c]coumarin compounds derived from salicylaldehydes, malononitrile, and ethyl acetoacetate is reported. The reaction is conducted on grinding over MgO at room temperature resulting in good yields.
MATERIALS
Product Number
Brand
Product Description