SRP4365

VEGF165 from rat

recombinant, expressed in E. coli, ≥98% (SDS-PAGE)

• Synonym(s): MGC70609, VEGF, VEGF-A, VPF, Vascular endothelial growth factor A, Vascular permeability factor
• UNSPSC Code: 12352202
• NACRES: NA.32

Properties

• biological source: rat
• recombinant: expressed in E. coli
• Assay: ≥98% (SDS-PAGE)
• form: lyophilized
• mol wt: ~38.4 kDa
• packaging: pkg of 10 μg
• storage condition: avoid repeated freeze/thaw cycles
• impurities: endotoxin, tested
• NCBI accession no.: P16612
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: rat ... Vegfa(83785)

Description

General description

VEGF165 (vascular endothelial growth factor 165), also known as VEGF-A, is a homodimeric glycoprotein and is expressed as multiple splice variants. Recombinant rat VEGF is a double, non-glycosylated, polypeptide containing 164 amino acids and having a molecular mass of 38.4kDa.

Application

VEGF165 (vascular endothelial growth factor 165) has been used to study the effects of VEGF on the morphology and survival of neurons and glial cells.

Biochem/physiol Actions

VEGF165 (vascular endothelial growth factor 165) has been shown to have pro-angiogenic properties. It has a role in the proliferation of endothelial cells and neuroprotection.

Physical form

Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, pH 7.5

Reconstitution

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

Reconstitute in water to a concentration of 0.1-1.0 mg/mL. The solution can then be diluted into other aqueous buffers.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable