317861

Phenyl isothiocyanate

99%, for protein sequencing

• Synonym(s): PITC
• Linear Formula: C₆H₅NCS
• CAS Number: 103-72-0
• Molecular Weight: 135.19
• Beilstein: 471392
• EC Number: 203-138-1
• MDL number: MFCD00004798
• UNSPSC Code: 12352100
• PubChem Substance ID: 57648607
• NACRES: NA.21

Properties

• type: for protein sequencing
• Assay: 99%
• form: liquid
• refractive index: n20/D 1.6515 (lit.)
• bp: 218 °C (lit.); 221 °C
• mp: −21 °C (lit.)
• solubility: water: insoluble
• density: 1.132 g/mL at 20 °C (lit.)
• storage temp.: 2-8°C
• SMILES string: S=C=Nc1ccccc1
• InChI: 1S/C7H5NS/c9-6-8-7-4-2-1-3-5-7/h1-5H
• InChI key: QKFJKGMPGYROCL-UHFFFAOYSA-N

Description

Application

Used for derivatizing N-terminal amino acids of proteins for automated sequential analysis. Synthon for dithiadiazafulvalenes.

Derivatizing reagent for primary and secondary amines. Used in sequencing peptides by Edman degradation and in amino acid analyses by HPLC.

Safety Information

• Pictograms: GHS06,GHS08,GHS05
• Signal Word: Danger
• Hazard Statements: H301,H314,H317,H334
• Precautionary Statements: P261 - P272 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point(F): 190.4 °F - closed cup
• Flash Point(C): 88 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves