178462-M

Apolipoprotein C-II, Human Plasma, Very Low-Density Lipoprotein

Native apolipoprotein C-II from human plasma. Found primarily in VLDL and chylomicrons. Functions as a cofactor for lipoprotein lipase.

• Synonym(s): Apo C-II
• UNSPSC Code: 12352202

Properties

• Quality Level: 100
• Assay: ≥95% (SDS-PAGE)
• form: lyophilized
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• solubility: water: soluble
• storage temp.: −20°C

Description

General description

Native apolipoprotein C-II from human plasma. Found primarily in VLDL and chylomicrons. Functions as a cofactor for lipoprotein lipase. Elevated serum levels of Apo C-II are common in type I, III, IV, and V hyperlipoproteinemia. Low serum concentrations of Apo C-II are indicative of nephrotic syndrome (Tangier’s Disease).

Native apolipoprotein C-II from human plasma. Found primarily in VLDL and chylomicrons. Functions as a cofactor of lipoprotein lipase. Elevated serum levels of Apo C-II are often present in type I, III, IV and V hyperlipoproteinemia. Low serum concentrations of Apo C-II are indicative of nephrotic syndrome (Tangier disease).

Warning

Toxicity: Standard Handling (A)

Physical form

Lyophilized from 10 mM NH₄HCO₃, pH 7.4.

Preparation Note

Please refer to vial label for lot-specific volume prior to lyophilization.

Other Notes

Brunzell, J.D. 1989. in The Metabolic Basis of Inherited Disease,6th Edition (Scriver, G.R., ed.) p. 1165, McGraw Hill, New York.
Le, N.A., et al. 1988. J. Lipid Res. 29, 669.
Jackson, R.L., and Holdsworth, G. 1986. Methods Enzymol.128, Chapter 14.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable