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668435

Sigma-Aldrich

1,2-Bis[(2S,5S)-2,5-diisopropylphospholano]ethane

kanata purity

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About This Item

Empirical Formula (Hill Notation):
C22H44P2
CAS Number:
Molecular Weight:
370.53
MDL number:
UNSPSC Code:
12352005
PubChem Substance ID:
NACRES:
NA.22

Quality Level

form

solid

mp

67-72 °C

functional group

phosphine

SMILES string

CC(C)[C@H]1P(CCP2[C@H](C(C)C)CC[C@H]2C(C)C)[C@H](C(C)C)CC1

InChI

1S/C22H44P2/c1-15(2)19-9-10-20(16(3)4)23(19)13-14-24-21(17(5)6)11-12-22(24)18(7)8/h15-22H,9-14H2,1-8H3/t19-,20-,21-,22-/m1/s1

InChI key

IRVIFEWWPYKALC-GXRSIYKFSA-N

General description

1,2-Bis[(2S,5S)-2,5-diisopropylphospholano]ethane is a chiral C2-symmetric ligand, which on ligation with metal complexes forms active catalysts for asymmetric hydrogenation.

Legal Information

Sold in collaboration with Kanata Chemical Technologies Inc. for research purposes only. These compounds were made and sold under license from E.I. du Pont de Nemours and Company, which license does not include the right to use the compounds in producing products for sale in the pharmaceutical field.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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A mass spectrometric method for rapidly assaying the chiral selectivities of the copper (I) complexes of C2-symmetric ligands.
Davis MC and Gronert S.
Journal of Mass Spectrometry : Jms, 50(11), 1279-1287 (2015)

Articles

Asymmetric hydrogenation reactions represent the ideal process for the commercial manufacture of single-enantiomer compounds, because of the ease by which these robust procedures can be scaled up and because of the low levels of byproducts generated in these asymmetric hydrogenations.

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